After 3 years, the 'Applying Wolbachia to Eliminate Dengue' Randomised Controlled Trial conducted in Yogyakarta City shows incidence of dengue cases in intervention areas decreased by 77% compared with untreated areas within the study site.
The World Mosquito Program is working in and around Yogyakarta to protect communities from mosquito-borne diseases like dengue, Zika, chikungunya and yellow fever.
Following encouraging results from our initial trials in Sleman and Bantul Districts in 2014, a large-scale efficacy study to evaluate the impact of our Wolbachia method on dengue transmission is now underway in Yogyakarta City. The project is working closely with government, health authorities and local communities to undertake this work, which includes a quasi-experimental study and the first randomised controlled trial of Wolbachia for dengue control.
The second phase of releases in Yogyakarta City was in a cluster randomised controlled trial called the AWED trial (Applying Wolbachia to Eliminate Dengue). This trial is designed to rigorously evaluate the impact of Wolbachia on the transmission of dengue and other mosquito-borne diseases. Releases in the AWED trial were conducted in 2017. Participant recruitment commenced in January 2018, and the trial is ongoing until 2020.
The community has been enthusiastically supporting the project in Yogyakarta City, with more than 12,400 volunteers helping to release mosquitoes, host bug traps and promote the project. Almost 10,000 volunteers helped to release mosquitoes – an amazing effort!
We’ve been working with communities in Indonesia since 2012 to help prevent mosquito-borne diseases. Read our progress updates to see our latest news.